Treating the Underlying Causes of Age-Related Disease
At Underdog, we’re developing drugs to prevent common age-related conditions such as atherosclerosis, heart attack and stroke by addressing the root cause of the build-up of arterial plaque.
Our technology removes plaque by clearing forms of non-degradable cholesterol
accumulating within cells in the arterial walls.
Our vision is an affordable, easy-to-use treatment to prevent disease for everyone.
Our products are based on novel derivatives of a well-known, safe compound, and a new way of looking at cardiovascular disease created through a SENS Research Foundation program.
Curing age-related disease
through damage repair
using simple, direct, rationally designed drugs
... starting with
the first true disease-modifying treatment for atherosclerosis
... based on
a novel class of well-known, safe compounds called cyclodextrins
... driven by
a new perspective on cardiovascular disease
... created through
a long-running SENS Research Foundation program
with two-years applied development in an internal, virtual start-up
to carry development through Investigational New Drug application filing
Underdog is continuing to develop technology created at SENS Research Foundation to treat, cure, and reverse atherosclerosis.
Underdog Pharmaceuticals, Inc., is pursuing a mission to treat the underlying causes of age-related disease. The company develops simple and direct interventions targeting toxic forms of cholesterol, using rationally designed molecules, to provide the first true disease-modifying treatments for age-related diseases such as atherosclerosis, hypercholesterolemia, heart failure, and macular degeneration.
